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Evaluation of right ventricular function using single-beat three-dimensional echocardiography in neonate
Kazuhiro Watanabe1, Ikuo Hashimoto, Keijiro Ibuki
1Department of Pediatrics, Toyama City Hospital, 2-1 Hokubu Mach, Imaizumi, Toyama City, Toyama, Japan.
Pediatric Cardiology
|January 16, 2015
Summary
Newly developed single-beat three-dimensional echocardiography (sb3DE) allows for right ventricular (RV) systolic function assessment in neonates. While sb3DE shows promise, RV stroke volume measurements require further refinement for accurate neonatal application.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Echocardiography
Background:
- Assessing right ventricular (RV) systolic function in neonates is crucial for early diagnosis and management of cardiac conditions.
- Traditional echocardiography methods may have limitations in neonatal RV volume and function assessment.
- Novel imaging techniques are needed to improve the accuracy and efficiency of neonatal cardiac evaluation.
Purpose of the Study:
- To evaluate the feasibility and accuracy of newly developed single-beat three-dimensional echocardiography (sb3DE) for assessing RV systolic function in neonates.
- To compare sb3DE-derived RV volumes and stroke volume with conventional echocardiographic methods.
- To explore the correlation between sb3DE-derived parameters and tricuspid annular plane systolic excursion (TAPSE).
Main Methods:
- A cohort of 15 healthy or premature neonates (0-53 days) was enrolled.
- Siemens ACUSON SC2000 echocardiography with a 4Z1c transducer was used for single-beat full volume acquisition without ECG gating.
- RV end-diastolic volume (RVEDV), RV end-systolic volume (RVESV), RV ejection fraction (RVEF), and 3D RV stroke volume (3D-RVSV) were computed.
- Doppler-derived RV stroke volume (Doppler-RVSV) and TAPSE were measured for comparison.
Main Results:
- sb3DE enabled successful three-dimensional acquisition of RV volume in neonates without ECG gating.
- A good correlation was observed between 3D-RVSV and Doppler-RVSV (r = 0.77).
- Bland-Altman analysis indicated a tendency for 3D-RVSV to underestimate Doppler-RVSV by an average of 1.78 ml.
- TAPSE positively correlated with 3D-RVEF (r = 0.58, P = 0.038).
Conclusions:
- Newly developed sb3DE is a feasible tool for assessing RV volume and systolic function in neonates.
- Current sb3DE measurements of RV stroke volume in neonates may require further optimization due to underestimation.
- sb3DE holds potential for improving neonatal cardiac assessment, complementing existing echocardiographic parameters like TAPSE.
