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Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
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Structure-Based Drug Design of Novel Potent and Selective Tetrahydropyrazolo[1,5-a]pyrazines as ATR Inhibitors

Paul A Barsanti1, Robert J Aversa1, Xianming Jin1

  • 1Global Discovery Chemistry Oncology, Novartis Institutes for Biomedical Research , 5300 Chiron Way, Emeryville, California 94608, United States.

ACS Medicinal Chemistry Letters
|January 16, 2015
PubMed

Keywords:
ATRCYP3A4 TDIFsp3deuteriumstructure-based drug design

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