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Updated: Apr 18, 2026

Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3
Published on: December 27, 2010
Stimulant use patterns and HIV transmission risk among HIV-serodiscordant male couples
Kristi E Gamarel1, Sarah E Woolf-King, Adam W Carrico
1*Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI; Departments of †Medicine; and ‡Nursing, University of California, San Francisco, San Francisco, CA.
Background:
Substance use is strongly linked to HIV risk, and members of couples can have a powerful influence on each other's health behaviors. We examined whether couple-level patterns of stimulant use were differentially associated with engaging in condomless anal intercourse with primary partners and outside partners.
Methods:
Members of HIV serodiscordant male couples (N = 117 couples, 232 men) completed surveys, and HIV-positive men had blood drawn for viral load.
Results:
Results revealed that stimulant use by only one partner in the couple was associated with a decrease in the odds of engaging in condomless anal sex with one's primary partner (AOR = 0.09, 95% CI: 0.01, 0.89). When both partners reported stimulant use, the HIV-negative partner had an increase in the odds of condomless sex with outside partners (AOR = 6.68, 95% CI: 1.09, 8.01).
Conclusions:
Understanding the role of couples' stimulant use patterns in HIV transmission risk is an important area for future research and intervention.
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