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Characterization and in vivo distribution of 99mTc- and 111In-labelled magnetite
S W Bligh1, P J Sadler, J A Marriott
1Department of Chemistry, Birkbeck College, University of London, England.
International Journal of Radiation Applications and Instrumentation. Part A, Applied Radiation and Isotopes
|January 1, 1989
Abstract:
Magnetite (Fe3O4) particles 0.1-0.5 microns in diameter doped with either 99mTc or 111In have been prepared and characterized by electron microscopy and Mössbauer spectroscopy. The time courses of their distributions after injection into rats were determined, including studies by gamma-camera imaging; the main targets were the liver and lung. The radiolabelled magnetic agents may be of value in research studies combining radio- and magnetic resonance imaging procedures.