First Indian single center experience with pipeline embolization device for complex intracranial aneurysms

Area of Science:

• Endovascular neurosurgery
• Cerebrovascular disease management
• Medical device innovation

Background:

• Flow diversion using endoluminal sleeve, the flow diverter stent, is a novel therapy for complex aneurysms.
• This study presents the first Indian single-center experience with the Pipeline Embolization Device (PED).
• Six-month follow-up results for five patients treated with PED are reported.

Observation:

• Five complex or recurrent intracranial aneurysms in five patients were treated with PED.
• Follow-up included magnetic resonance angiography (MRA) at 4 weeks and conventional angiography at 6 months.
• Feasibility, complications, clinical outcome, and angiographic results were analyzed.

Findings:

• Complete aneurysm sac occlusion was observed in 100% of cases at 6 months.
• Side branch ostia covered by the PED remained patent in all treated patients (100%).
• No major neurological morbidity or mortality occurred; one patient had a minor, partially improved neurological disability.

Implications:

• The Pipeline Embolization Device is technically feasible, safe, and provides definitive vascular reconstruction for complex and recurrent aneurysms.
• PED can be used without concern for occlusion of covered eloquent side branches and perforators.
• This approach represents a significant advancement in treating challenging cerebrovascular lesions.