Related Experiment Video
Updated: Apr 18, 2026

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
Published on: December 10, 2013
Relationship between meteorological conditions and respiratory syncytial virus in a tropical country
C E Rodriguez-Martinez1, M P Sossa-Briceño2, R Acuña-Cordero3
1Department of Pediatrics,School of Medicine,Universidad Nacional de Colombia.
Insights
Higher average temperatures and increased rainfall are linked to more respiratory syncytial virus (RSV) infections in children hospitalized with acute lower respiratory infection (ALRI) in Bogota. These findings highlight key meteorological factors influencing RSV outbreaks.
Area of Science:
- Environmental Health
- Pediatric Infectious Diseases
- Climatology
Background:
- Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory infection (ALRI) in young children globally.
- Understanding environmental factors influencing RSV transmission is crucial for public health interventions, especially in tropical urban settings.
- Bogota, Colombia, experiences distinct climatic variations that may impact the incidence of pediatric respiratory illnesses.
Purpose of the Study:
- To identify specific meteorological conditions associated with RSV infections in hospitalized children in Bogota.
- To analyze the correlation between monthly climate variations and the number of RSV cases.
- To provide data for localized RSV outbreak prediction and prevention strategies.
Main Methods:
- An analytical cross-sectional study design was employed.
- Data on monthly RSV infections and meteorological variables (temperature, humidity, rainfall, wind speed, solar radiation) were collected from January 2010 to April 2011.
- Multivariate analysis was used to determine independent associations between meteorological factors and RSV infections in children under 3 years old.
Main Results:
- A total of 1548 children were included, with 77.1% diagnosed with RSV during March-May.
- Monthly average temperature (IRR 3.14, P=0.001) and rainfall (IRR 1.008, P=0.048) were independently associated with the number of RSV infections.
- These associations remained significant after controlling for wind speed, relative humidity, and solar radiation.
Conclusions:
- Average temperature and rainfall are the primary meteorological drivers associated with RSV isolation in Bogota.
- Findings suggest that climate monitoring can aid in predicting RSV surges in this tropical urban environment.
- This research contributes to understanding the environmental epidemiology of RSV in Latin American cities.
Abstract:
This study aimed to determine which meteorological conditions are associated with respiratory syncytial virus (RSV) isolates in a population of children hospitalized with acute lower respiratory infection (ALRI) in Bogota, Colombia. In an analytical cross-sectional study, links were examined between the number of monthly RSV infections and monthly average climatic variation (temperature, relative humidity, rainfall, wind speed, solar radiation) between 1 January 2010 and 30 April 2011 in a population of hospitalized children aged <3 years with ALRI caused by RSV. Out of a total of 1548 children included in the study (mean age 9·2 ± 8·5 months), 1194 (77·1%) presented RSV infection during the 3-month period from March to May. In the multivariate analysis, after controlling for wind speed, relative humidity, and solar radiation, monthly average temperature [incident rate ratio (IRR) 3·14, 95% confidence interval (CI) 1·56-6·30, P = 0·001] and rainfall (IRR 1·008, 95% CI 1·00-1·01, P = 0·048) were independently associated with the monthly number of RSV infections. In conclusion, in Bogota, a tropical Latin American city, average temperature and rainfall are the meteorological variables most strongly associated with RSV isolation in children hospitalized with ALRI in the city.
Related Concept Videos
Common Respiratory Disorders
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
Microbiota of the Respiratory Tract
Influenza
Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Factors Affecting Pulmonary Ventilation
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...

