Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

320
A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
320
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

277
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
277
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

464
Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
464
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

262
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
262
Pneumothorax-II01:27

Pneumothorax-II

852
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
852
Chronic Obstructive Pulmonary Disease-V: Management01:29

Chronic Obstructive Pulmonary Disease-V: Management

3.1K
Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
3.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

OMA1 protects from liver injury and tumorigenesis during aging by controlling hepatic immunogenicity.

The EMBO journal·2026
Same author

SUCNR1 coordinates metabolic flux, mitochondrial function, and nutrient-dependent adaptation in hepatocytes.

Science advances·2026
Same author

Publisher Correction: Polyamine-dependent metabolic shielding regulates alternative splicing.

Nature·2026
Same author

Polyamine-dependent metabolic shielding regulates alternative splicing.

Nature·2026
Same author

BoltzGen: Toward Universal Binder Design.

bioRxiv : the preprint server for biology·2025
Same author

Structural basis for the recruitment and selective phosphorylation of Akt by mTORC2.

Science (New York, N.Y.)·2025

Related Experiment Video

Updated: Jan 9, 2026

Pulmonary Embolism III: Nursing Management
01:27

Pulmonary Embolism III: Nursing Management

Published on: June 19, 2025

320

Nutrient-sensing mechanisms and pathways.

Alejo Efeyan1, William C Comb1, David M Sabatini2

  • 11] Whitehead Institute for Biomedical Research, Nine Cambridge Center, Cambridge, Massachusetts 02142, USA. [2] Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA. [3] David H. Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA. [4] Broad Institute, Seven Cambridge Center, Cambridge, Massachusetts 02142, USA.

Nature
|January 17, 2015
PubMed
Summary
This summary is machine-generated.

Organisms sense and respond to nutrient availability, a fundamental survival mechanism. This nutrient sensing regulates metabolism, impacting processes from storage to autophagy, and is crucial for preventing metabolic diseases.

More Related Videos

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Published on: June 19, 2025

277
Pulmonary Embolism I: Introduction
01:29

Pulmonary Embolism I: Introduction

Published on: June 19, 2025

464

Related Experiment Videos

Last Updated: Jan 9, 2026

Pulmonary Embolism III: Nursing Management
01:27

Pulmonary Embolism III: Nursing Management

Published on: June 19, 2025

320
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Published on: June 19, 2025

277
Pulmonary Embolism I: Introduction
01:29

Pulmonary Embolism I: Introduction

Published on: June 19, 2025

464

Area of Science:

  • Cellular Biology
  • Metabolism
  • Evolutionary Biology

Background:

  • Life requires sensing and responding to environmental nutrient fluctuations.
  • Nutrient scarcity drives evolutionary adaptations in cellular processes.
  • Hormonal signals integrate nutrient detection pathways at the organismal level.

Purpose of the Study:

  • To explore the integration of nutrient-sensing pathways.
  • To understand the organismal coordination of nutrient detection.
  • To highlight the role of nutrient sensing in metabolic health and disease.

Main Methods:

  • Review of cellular nutrient detection pathways (sugars, amino acids, lipids).
  • Analysis of hormonal signal integration in nutrient response.
  • Examination of metabolic regulation during nutrient abundance and scarcity.

Main Results:

  • Nutrient sensing pathways control anabolism and storage during abundance.
  • Scarcity triggers homeostatic mechanisms like autophagy for internal store mobilization.
  • Dysregulation of nutrient-sensing pathways is linked to human metabolic diseases.

Conclusions:

  • Nutrient sensing is a fundamental biological process essential for survival.
  • Integrated nutrient sensing pathways are critical for metabolic homeostasis.
  • Understanding these pathways offers insights into metabolic disease pathogenesis.