Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Varicose Veins II: Diagnostic Studies and Interprofessional Care

Varicose Veins II: Diagnostic Studies and Interprofessional Care

Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A modified Delphi consensus on tenosynovial giant cell tumour and giant cell tumour of bone : a report from the Birmingham Orthopaedic Oncology Meeting (BOOM).

The bone & joint journal·2026

Same author

Sclerotherapy for Aneurysmal Bone Cyst in Canine.

Veterinary medicine and science·2026

Same author

A prospective observational study to assess the compliance to enhanced recovery protocols among patients undergoing bone and soft tissue cancer surgeries and their postoperative outcomes.

Indian journal of surgical oncology·2026

Same author

Complications of PI to PIII hemipelvic resections for intermediate and malignant tumours : a systematic review and meta-analysis.

Bone & joint open·2026

Same author

Favourable outcomes of extraskeletal Ewing sarcoma treated on a non-dense chemotherapy backbone with inclusion of radiotherapy for local control.

Ecancermedicalscience·2026

Same author

Long-term outcomes with non-dose dense chemotherapy for Ewing sarcoma - a follow up of the cohort treated with EFT-2001 protocol.

Ecancermedicalscience·2026

Same journal

Functional Outcomes and Complications of Dual Mobility Versus Fixed-Bearing Total Hip Arthroplasty in Femoral Neck Fractures over 55 Years: A Retrospective Analysis.

Indian journal of orthopaedics·2026

Same journal

Prevalence of Atherosclerosis in Femoral and Popliteal Arteries in Advanced Osteoarthritis Knee: A Cross Sectional Ultrasound Study.

Indian journal of orthopaedics·2026

Same journal

Efficacy of Pre-operative Physical Therapy on Total Knee Replacements: A Systematic Review of Randomized Controlled Trials.

Indian journal of orthopaedics·2026

Same journal

Predictive Value of Radiographs in Assessment of Post-Hemiarthroplasty Recovery Following Femoral Neck Fractures Amongst the Elderly.

Indian journal of orthopaedics·2026

Same journal

Reoperation Rates Following Lumbar Decompression Surgery at Three or More Levels.

Indian journal of orthopaedics·2026

Same journal

Morphological Analysis of Thoracolumbar Vertebrae Based on Age and Gender in Indonesia Population: A Computed Tomography-Based Study.

Indian journal of orthopaedics·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 18, 2026

Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity

Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity

Published on: January 31, 2025

Limb salvage: When, where, and how?

¹Department of Orthopaedic Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Indian Journal of Orthopaedics

|January 17, 2015

Summary

This summary is machine-generated.

Limb salvage surgery for musculoskeletal sarcomas has advanced significantly, moving beyond amputation. Modern techniques focus on function preservation, skeletal stability, and optimal wound coverage for better patient recovery and outcomes.

Keywords:

Bone neoplasm Bone tumor megaprosthesis prosthesis reconstruction reconstructive surgical procedure

More Related Videos

Orthotopic Hind-Limb Transplantation in Rats

Orthotopic Hind-Limb Transplantation in Rats

Published on: July 12, 2010

Taking the Next Step: a Neural Coaptation Orthotopic Hind Limb Transplant Model to Maximize Functional Recovery in Rat

Taking the Next Step: a Neural Coaptation Orthotopic Hind Limb Transplant Model to Maximize Functional Recovery in Rat

Published on: August 30, 2020

Related Experiment Videos

Last Updated: Apr 18, 2026

Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity

Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity

Published on: January 31, 2025

Orthotopic Hind-Limb Transplantation in Rats

Orthotopic Hind-Limb Transplantation in Rats

Published on: July 12, 2010

Taking the Next Step: a Neural Coaptation Orthotopic Hind Limb Transplant Model to Maximize Functional Recovery in Rat

Taking the Next Step: a Neural Coaptation Orthotopic Hind Limb Transplant Model to Maximize Functional Recovery in Rat

Published on: August 30, 2020

Area of Science:

Orthopedic Oncology
Surgical Reconstruction

Background:

Musculoskeletal sarcomas historically led to amputation.
Current treatment emphasizes limb salvage and function preservation.

Purpose of the Study:

To review surgical margins and resection principles for sarcomas.
To summarize reconstruction modalities and challenges after limb salvage.
To discuss reconstruction in skeletally immature patients.

Main Methods:

Review of oncologic surgical principles.
Summary of current and emerging reconstruction techniques.
Discussion of challenges in pediatric limb salvage.

Main Results:

Function-preserving resections and complex reconstructions represent major advances.
Achieving adequate resection while preserving function and cosmesis is challenging.
Multidisciplinary efforts and centralized expertise improve outcomes.

Conclusions:

Limb salvage surgery requires balancing oncologic safety with functional and aesthetic restoration.
Patient counseling regarding potential complications is crucial.
Centralized expertise in regional centers enhances outcomes for musculoskeletal sarcoma patients.