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Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection
Published on: August 23, 2022
Effect of green tea on the second degree burn wounds in rats
Mohammad Javad Fatemi1, Babak Nikoomaram2, Amir Asadollah Khajeh Rahimi2
1Departments of Plastic and Reconstructive Surgery, Hazrat Fateme Hospital and Burn Research Center, Iran University of Medical Sciences, Tehran, Iran.
Background:
Various studies indicate that the green tea has anti-inflammatory and anti-oxidative properties. Moreover, a few studies have been carried out that demonstrate beneficial effects of green tea on burned patients.
Materials And Methods:
In this study, green tea, Vaseline, and silver sulfadiazine dressings were used as first-aid treatment to deep dermal contact burns in rats, compared with a control of nothing. After creating second-degree burn on the dorsum of rats, the treatments were applied for 15 min in four groups. Wound dressing changes were daily. Macroscopic study was performed on days 1, 3, 7, and 14 by using a digital camera and software processing of photos. Microscopic examination was done by pathologic evaluation of skin specimens on day 14.
Results:
We observed that green tea usage significantly decreased burn size in comparison to the control group (P = 0.004).
Conclusion:
Green tea is effective on healing process of second degree burn wounds.

