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Published on: May 26, 2015
Catheter ablation of atrial fibrillation in the elderly
Louiza Lioni1, Konstantinos P Letsas1, Michael Efremidis1
1Second Department of Cardiology, Laboratory of Cardiac Electrophysiology, Evangelismos General Hospital of Athens, Athens 10676, Greece.
Insights
Catheter ablation for atrial fibrillation (AF) is safe and effective in elderly patients. This procedure offers a viable alternative for older individuals experiencing symptomatic AF.
Area of Science:
- Cardiology
- Electrophysiology
- Geriatric Medicine
Background:
- Atrial fibrillation (AF) catheter ablation is a key treatment, yet adoption in the elderly is limited.
- The safety and efficacy of AF catheter ablation in older populations require further investigation.
Purpose of the Study:
- To evaluate the safety and effectiveness of catheter ablation for atrial fibrillation in elderly patients.
Main Methods:
- A study involving 316 patients with paroxysmal AF undergoing left atrial ablation.
- Comparison of outcomes between 95 elderly patients (≥65 years) and 221 younger patients (<65 years).
- Mean follow-up of 34.0 ± 15.1 months to assess arrhythmia recurrence and procedural complications.
Main Results:
- Arrhythmia recurrence was observed in 57.9% of elderly patients versus 67.4% of younger patients (P=0.169).
- Procedural complications were infrequent in both age groups.
- Independent predictors of AF recurrence in the elderly included left atrial diameter, hypertension, dyslipidemia, and coronary artery disease.
Conclusions:
- Catheter ablation for AF demonstrates safety and efficacy in older individuals.
- Invasive ablation strategies should be considered for symptomatic elderly patients with AF.
Background:
Atrial fibrillation (AF) catheter ablation has emerged as a promising treatment strategy for AF, but has not been widely adopted in the elderly population. The present study aimed to determine the safety and efficacy of AF catheter ablation in the elderly population.
Methods And Results:
The study population consisted of 316 patients with paroxysmal AF who underwent left atrial ablation. Ninety-five patients were ≥ 65 years (48 males, mean age 68.9 ± 3.0 years old) and 221 patients were < 65 years old (130 males, mean age 52.5 ± 10.4 years old). After a mean follow-up period of 34.0 ± 15.1 months, 55 (57.9%) patients in the elderly group were free from arrhythmia recurrence compared with 149 (67.4%) patients in the younger group (P = 0.169). Procedural complications were uncommon in both study groups. In logistic regression analysis, left atrial diameter (P = 0.003), hypertension (P = 0.001), dyslipidemia (P = 0.039), and coronary artery disease (P = 0.018) were independent predictors of AF recurrence in the elderly population.
Conclusions:
Catheter ablation of AF is safe and effective in older patients. Invasive strategies should be considered as an alternative choice in symptomatic elderly patients with AF.
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