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Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
Published on: July 17, 2020
Chromone derivatives from a sponge-derived strain of the fungus Corynespora cassiicola
Dong-Lin Zhao1, Chang-Lun Shao, Li-She Gan
1Key Laboratory of Marine Drugs, The Ministry of Education of China, School of Medicine and Pharmacy, and §Institute of Evolution & Marine Biodiversity, Ocean University of China , Qingdao 266003, People's Republic of China.
Abstract:
Twelve new chromone derivatives, corynechromones A-L (1-12), were isolated from the sponge-derived fungus Corynespora cassiicola XS-200900I7. Among them, 1/2, 3/4, 5/6, and 7/8 were pairs of epimers. The planar structures were determined by extensive NMR spectroscopic data. The absolute configurations of 1-10 were assigned by the modified Mosher's method and TDDFT ECD calculations together with comparison of their CD spectra. These are the first chromone derivatives reported from the genus Corynespora. A possible rule to determine the absolute configurations at C-2 in chromone derivatives by CD was proposed.
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