Prosthetic devices with nanostructurated surfaces for increased resistance to microbial colonization
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Updated: Apr 18, 2026

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
Published on: August 4, 2018
Alina M Holban, Alexey Iordanskii, Alexandru M Grumezescu
1Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, Politehnica University of Bucharest, Polizu Street no 1-7, 011061 Bucharest, Romania. grumezescu@yahoo.com.
Abstract:
This review highlights and discusses the impact of nanotechnology on the inhibition of microbial colonization and biofilm development on modified surface prosthetic devices. In the first part of the paper the current status of infections related to prosthetic devices and the inquiries resulting from the increased number of patients with these infections are briefly reviewed. Next we discuss several aspects about the implication of nanotechnology in prosthetic devices surface modification and its impact on the prevention of infections. The main aspects regarding the biocompatibility and the application of these nanomodified prosthetic devices in tissue engineering are also highlighted.
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