Antimicrobial Chitosan based formulations with impact on different biomedical applications

Area of Science:

• Biomaterials Science
• Polymer Chemistry
• Nanotechnology

Background:

• Chitosan is a biodegradable and biocompatible polymer derived from crustacean shells.
• Its unique physico-chemical properties make it suitable for various industrial and biomedical applications.
• Chitosan's ability to form complexes and its stability at physiological pH are advantageous for drug delivery.

Purpose of the Study:

• To review the applications of chitosan as a drug delivery component.
• To describe recent technologies utilizing chitosan for nanostructured systems.
• To explore the potential of chitosan in novel, eco-friendly biomedical applications.

Main Methods:

• Literature review of chitosan-based drug delivery systems.
• Analysis of nanostructured systems with antimicrobial effects.
• Discussion of chitosan's properties relevant to biomedical applications.

Main Results:

• Chitosan is a versatile polymer for developing nanoparticles, microparticles, and hydrogels.
• Chitosan-based nanocomposites exhibit stability at physiological pH, crucial for drug delivery.
• Recent technologies focus on nanostructured chitosan systems with antimicrobial properties.

Conclusions:

• Chitosan is a preferred candidate for green biomedical applications, particularly in drug delivery.
• Nanostructured chitosan systems offer potential for efficient and eco-friendly therapeutic solutions.
• Further research into chitosan-based technologies can lead to innovative biomedical products.