Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Mechanisms by which proline reductase of <i>Clostridioides difficile</i> promotes efficient metabolism and disease progression <i>in vivo</i>.

mBio·2026

Same author

Association between blenderized tube feeds and differential oropharynx, stomach, and stool microbiome signatures relative to conventional formula feeds in children fed via enteral tube: A cross-sectional study.

JPEN. Journal of parenteral and enteral nutrition·2026

Same author

Leveraging the global genomic epidemiology of carbapenemase-producing <i>Klebsiella pneumoniae</i> to inform infection prevention in Tunisian hospitals.

Antimicrobial agents and chemotherapy·2026

Same author

Attomolar fecal cytokine profiling reveals gut immune dynamics and disease states.

bioRxiv : the preprint server for biology·2026

Same author

<i>Blautia wexlerae</i> Transforms Dietary Fatty Acids to Activate Enteroendocrine Signaling and Improve Metabolic Health in Mice and Humans.

bioRxiv : the preprint server for biology·2026

Same author

Genomic and clinical determinants of extraintestinal <i>Clostridium perfringens</i> infections in immunocompromised patients.

medRxiv : the preprint server for health sciences·2026

Same journal

Assessing Human Epidermal Growth Factor Receptor 2 in Urothelial Carcinoma: Insights From Clinical Practice Into Scoring Criteria, Histologic Subtypes, and Genomic Characteristics Across Disease Sites.

Archives of pathology & laboratory medicine·2026

Same journal

Cross-Reactivity of TPIT Antibody Clone OTI2G1 in Chordoma: Structural Mechanisms and Diagnostic Implications.

Archives of pathology & laboratory medicine·2026

Same journal

Paracoccidioidomycosis at Autopsy: A Case Series and Literature Review.

Archives of pathology & laboratory medicine·2026

Same journal

Accuracy of Cytology Diagnosis for Well Differentiated Neuroendocrine Tumors: Assessment by the College of American Pathologists Non-Gynecologic Slide Program.

Archives of pathology & laboratory medicine·2026

Same journal

Serum Immunofixation Electrophoresis Guidance Conflict: A Call to Harmonize.

Archives of pathology & laboratory medicine·2026

Same journal

In Reply.

Archives of pathology & laboratory medicine·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 18, 2026

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Published on: November 30, 2022

A Call to Standardize Preanalytic Data Elements for Biospecimens, Part II.

James A Robb, Lynn Bry, Patrick M Sluss

¹From the Department of Pathology, Brigham and Women's Hospital (Dr Bry), and the Department of Pathology, Massachusetts General Hospital (Dr Sluss), Boston; the Department of Pathology, MD Anderson Cancer Center, Houston, Texas (Dr Wagar); and the College of American Pathologists, Northfield, Illinois (Ms Kennedy). Dr Robb is a consulting pathologist in Boca Raton, Florida.

Archives of Pathology & Laboratory Medicine

|January 17, 2015

Summary

This summary is machine-generated.

This study identifies four essential preanalytic variables for clinical chemistry and microbiology biospecimens. These data fields enhance biospecimen quality for patient care and research.

More Related Videos

A Standardized Liquid Biopsy Preanalytical Protocol for Downstream Circulating-Free DNA Applications

A Standardized Liquid Biopsy Preanalytical Protocol for Downstream Circulating-Free DNA Applications

Published on: September 16, 2022

Author Spotlight: Standardizing Tissue Sampling in Proteomics and Immunochemistry Research

Author Spotlight: Standardizing Tissue Sampling in Proteomics and Immunochemistry Research

Published on: February 16, 2024

Related Experiment Videos

Last Updated: Apr 18, 2026

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Published on: November 30, 2022

A Standardized Liquid Biopsy Preanalytical Protocol for Downstream Circulating-Free DNA Applications

A Standardized Liquid Biopsy Preanalytical Protocol for Downstream Circulating-Free DNA Applications

Published on: September 16, 2022

Author Spotlight: Standardizing Tissue Sampling in Proteomics and Immunochemistry Research

Author Spotlight: Standardizing Tissue Sampling in Proteomics and Immunochemistry Research

Published on: February 16, 2024

Area of Science:

Biopathology
Clinical Informatics
Laboratory Medicine

Background:

High-quality biospecimens require accurate clinical annotation for patient care and research.
Preanalytic variables are crucial data points for biospecimen integrity.

Purpose of the Study:

To identify and define essential preanalytic variables for biospecimen annotation.
To expand the existing list of 170 variables with specific data fields for clinical chemistry and microbiology.

Main Methods:

A Biorepository Working Group, comprising experts in pathology and microbiology, identified and ranked additional preanalytic variables.
Potential negative impacts of missing variables were assessed.
Stakeholder review ensured comprehensive evaluation.

Main Results:

Four critical preanalytic variables were identified for clinical chemistry and microbiology biospecimens.
These variables provide a guide for implementing standardized annotation in biorepositories.

Conclusions:

Selecting appropriate preanalytic variables for biospecimens can be challenging.
The identified ranked list offers practical guidance for optimizing biospecimen annotation for research and clinical use.