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Updated: Apr 18, 2026
06:41
Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
Published on: October 24, 2018
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Extracorporeal membrane oxygenation-hemostatic complications.
Deirdre A Murphy1, Lisen E Hockings1, Robert K Andrews2
1Department of Intensive Care and Hyperbaric Medicine, Alfred Hospital, Melbourne, Australia; Department of Epidemiology and Preventative Medicine, School of Public Health, Monash University, Melbourne, Australia.
Transfusion Medicine Reviews
|January 18, 2015
Summary
Extracorporeal membrane oxygenation (ECMO) is increasingly used for critical cardiac and respiratory failure. This review details managing bleeding, clotting, and red blood cell complications during ECMO therapy.
Area of Science:
- Critical Care Medicine
- Cardiovascular Science
- Respiratory Medicine
Background:
- Extracorporeal membrane oxygenation (ECMO) utilization has risen due to technological advancements and successful applications in H1N1 influenza and cardiopulmonary resuscitation.
- Patients on ECMO represent a diverse group of critically ill individuals experiencing cardiac and respiratory failure.
- Hemorrhagic and thrombotic complications are significant contributors to morbidity and mortality in ECMO patients.
Purpose of the Study:
- To review the mechanisms of hemostatic, thrombotic, and hemolytic complications in patients undergoing ECMO.
- To outline current management strategies for these complications during ECMO support.
Main Methods:
- Literature review focusing on ECMO complications.
- Synthesis of information regarding pathophysiology and clinical management.
Main Results:
- Detailed explanation of bleeding risks and management protocols.
- Discussion of thrombotic events and their prevention/treatment.
- Overview of hemolytic complications associated with ECMO.
Conclusions:
- Effective management of hemostatic, thrombotic, and hemolytic complications is crucial for improving outcomes in ECMO patients.
- Continued research and technological innovation are needed to further mitigate these risks.
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