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Related Experiment Video

Updated: Apr 18, 2026

Isolation, Processing and Analysis of Murine Gingival Cells

Isolation, Processing and Analysis of Murine Gingival Cells

Published on: July 2, 2013

Plasma cell gingivitis with severe alveolar bone loss.

Vivek Kumar¹, Amitandra Kumar Tripathi¹, Charanjit Singh Saimbi²

¹Department of Periodontology, Career Postgraduate Institute of Dental Sciences and Hospital, Lucknow, Uttar Pradesh, India.

BMJ Case Reports

|January 18, 2015

Summary

Plasma cell gingivitis, a rare hypersensitivity reaction, presents as inflamed gingiva. Surgical intervention managed a severe case with significant alveolar bone loss.

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Area of Science:

Dentistry
Oral Pathology

Background:

Plasma cell gingivitis is a rare, benign gingival condition.
It is characterized by erythematous, edematous gingiva, often extending to the mucogingival junction.
Considered a hypersensitivity reaction, it presents as diffuse, papillary lesions that bleed easily.

Observation:

A case study of a 42-year-old man with plasma cell gingivitis was presented.
Clinical presentation included diffuse, erythematous, and papillary gingival lesions with bleeding upon minimal trauma.
Severe alveolar bone loss was noted at the affected site.

Findings:

Histological examination confirmed the presence of plasma cells, leading to a diagnosis of plasma cell gingivitis.
The condition was associated with significant periodontal destruction, specifically severe alveolar bone loss.

Implications:

This case highlights the importance of histological diagnosis for plasma cell gingivitis.
Surgical intervention can be an effective management strategy for severe cases involving alveolar bone loss.
Understanding the hypersensitivity nature of plasma cell gingivitis is crucial for patient management and prevention.