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Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
Published on: April 9, 2019
22.8K
Recent advances in image-guided targeted prostate biopsy.
Anna M Brown1, Osama Elbuluk, Francesca Mertan
1Molecular Imaging Program, National Cancer Institute, NIH, Bethesda, MD, USA.
Abdominal Imaging
|January 19, 2015
Summary
Image-guided targeted prostate biopsy improves cancer detection and reduces low-grade tumor diagnoses. This review covers advances in MRI-guided, cognitive fusion, and MRI/ultrasound fusion biopsy techniques for better prostate cancer diagnosis.
Area of Science:
- Urology
- Oncology
- Medical Imaging
Background:
- Prostate cancer diagnosis relies on PSA screening and sextant biopsy, leading to overdiagnosis of low-grade and underdiagnosis of high-grade cancers.
- Clinically significant prostate cancer is defined by a Gleason score of 7 or higher.
Purpose of the Study:
- To review recent advances in image-guided targeted prostate biopsy techniques.
- To highlight improvements in detecting clinically significant prostate cancer while reducing low-grade tumor diagnoses.
Main Methods:
- Review of emerging image-guided targeted prostate biopsy approaches.
- Examination of in-bore MRI-guided biopsy.
- Analysis of cognitive fusion and MRI/transrectal ultrasound (TRUS) fusion-guided biopsy techniques.
Main Results:
- Multi-parametric magnetic resonance imaging (mpMRI) combined with targeted biopsy enhances detection of significant prostate cancer.
- Image-guided methods improve diagnostic accuracy compared to traditional biopsy techniques.
- Reduced diagnosis of indolent, low-grade prostate tumors is a key benefit.
Conclusions:
- Image-guided targeted biopsy represents a significant advancement in prostate cancer diagnosis.
- These techniques offer improved accuracy in identifying clinically relevant prostate cancers.
- Future research focuses on refining these advanced biopsy methods for optimal patient outcomes.
