Related Experiment Video
Updated: Apr 18, 2026

Robotic Duodenal Sleeve Resection for Gastrointestinal Stromal Tumor with Rare Exon 8 KIT Mutation Following Neoadjuvant Imatinib
Published on: April 3, 2026
Incidental finding of GIST during obesity surgery
Sonja Chiappetta1, Sophia Theodoridou, Christine Stier
1Department of Bariatric and Metabolic Surgery, Sana Klinikum Offenbach, Starkenburgring 66, 63069, Offenbach am Main, Germany, sonja1002@gmx.de.
Background:
The purpose of this study was to review the incidence of incidental gastrointestinal stromal tumors (GISTs) in a cohort of morbidly obese patients undergoing laparoscopic sleeve gastrectomy (LSG) or Roux-en-Y gastric bypass (RYGB), analyzing surgery indication, morbidity, and follow-up data.
Methods:
All cases with incidental GISTs found were reviewed.
Results:
Two thousand six hundred three patients underwent obesity surgery founding a gastric GIST in eight patients (incidence 0.31 %). Mean tumor size was 7.65 mm (range 2.5-13 mm) with the majority of the lesions located in the fundus of the stomach. All lesions had negative resection margins. At a mean follow-up of 30 months, all patients were disease-free.
Conclusion:
The long-term disease-free survival of 100 % in our study establishes laparoscopic wedge resection during RYGB and LSG as safe and effective in treating incidental gastric GISTs <2 cm.

