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Dramatic changes in muscle contractile and structural properties after 2 botulinum toxin injections

Viviane B Minamoto1, Kentaro P Suzuki1, Shannon N Bremner1

  • 1Department of Orthopaedic Surgery, University of California San Diego, La Jolla, California, USA.

Muscle & Nerve
|January 20, 2015
PubMed
Summary

Repeated onabotulinum toxin (BoNT) injections significantly amplify muscle paralysis effects compared to single doses. Serial BoNT administration results in over 95% torque reduction, indicating a potent cumulative impact on muscle function.

Keywords:
Botox®denervationfiber typemuscle physiologyneurotoxin

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