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Published on: September 20, 2024
Orthokeratology for myopia control: a meta-analysis
Jun-Kang Si1, Kai Tang, Hong-Sheng Bi
1*MD †PhD Department of Ophthalmology, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China (J-KS, KT); Department of Ophthalmology, Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China (H-SB, X-RW); and Eye Institute of Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China (D-DG, J-GG).
Orthokeratology appears to slow myopia progression in children. This meta-analysis found reduced axial length and vitreous chamber depth elongation in children undergoing orthokeratology treatment.
Area of Science:
- Ophthalmology
- Optometry
- Pediatric Eye Care
Background:
- Myopia progression is a significant concern in pediatric populations.
- Effective interventions are needed to control the increasing prevalence of myopia.
Purpose of the Study:
- To perform a meta-analysis evaluating the efficacy of orthokeratology in mitigating myopia progression in children.
- To synthesize existing research on orthokeratology's impact on refractive error development.
Main Methods:
- Comprehensive literature search across PubMed, Embase, and Cochrane Library.
- Methodological quality assessed using the Jadad score.
- Statistical analysis conducted using RevMan 5.2.6 software.
Main Results:
- Included seven studies (2 RCTs, 5 non-RCTs) with 435 children (ages 6-16) over 2 years.
- Significant reduction in axial length elongation: -0.26 mm (p < 0.001).
- Significant reduction in vitreous chamber depth elongation: -0.18 mm (p = 0.02).
Conclusions:
- Orthokeratology demonstrates potential as a method to slow myopia progression in children.
- Further large-scale research is recommended to confirm findings and assess long-term outcomes.
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