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Report of seven children with hepatopulmonary syndrome
Duygu Erge1, Mukadder Ayşe Selimoğlu, Cemşit Karakurt
1Division of Allergy, Department of Pediatrics, İnönü University Faculty of Medicine, Malatya, Turkey. duyguolmez@hotmail.com.
Insights
Hepatopulmonary syndrome (HPS) is a serious lung complication of liver disease. Early screening with pulse oximetry can help identify HPS in children, improving transplant eligibility and outcomes.
Area of Science:
- Pulmonary Medicine
- Hepatology
- Pediatric Gastroenterology
Background:
- Hepatopulmonary syndrome (HPS) is a significant pulmonary vascular complication associated with chronic liver disease and portal hypertension.
- Diagnosis relies on identifying hypoxemia and intrapulmonary shunting via imaging techniques.
- Timely diagnosis is crucial for improving patient outcomes and prioritizing liver transplant waiting lists.
Observation:
- This report details the clinical and laboratory findings of seven pediatric patients diagnosed with HPS.
- The study focuses on the presentation and follow-up of these young patients at a specialized center.
Findings:
- Pulse oximetry is a recommended non-invasive screening tool for detecting HPS.
- Accurate diagnosis through echocardiography or lung scans is essential for appropriate management.
Implications:
- Increased awareness and early screening for HPS in pediatric populations are vital.
- Prompt diagnosis and management can significantly impact the prognosis and transplant candidacy of children with liver disease.
Abstract:
Hepatopulmonary syndrome is an important pulmonary vascular complication of liver disease. Its diagnosis is based on the presence of hypoxaemia and the demonstration of intrapulmonary shunting by contrast-enhanced echocardiography or perfusion lung scanning. Awareness of this condition is critical to improve the outcomes of patients with chronic liver disease and/or portal hypertension because hepatopulmonary syndrome receives additional priority on the waiting list for transplantation. A non-invasive measurement of the blood oxygen saturation with pulse oximetry is recommended as a screening tool for this syndrome. The aim of this report was to present clinical and laboratory findings and follow-up of seven paediatric patients who were diagnosed with HPS at our centre.
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