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Updated: Apr 18, 2026
05:52
Prehospital Thrombolysis: A Manual from Berlin
Published on: November 26, 2013
22.6K
[Sonothrombolysis for acute ischemic stroke]
Revista Medica De Chile
|January 21, 2015
Summary
Sonothrombolysis (ST) is a safe and feasible stroke treatment in Chilean hospitals. This study shows ST can be performed in complex medical centers, achieving good patient outcomes.
Area of Science:
- Neurology
- Interventional Neurology
- Medical Technology
Background:
- Sonothrombolysis (ST) is an emerging treatment modality for stroke.
- Assessing the feasibility of ST in a Chilean hospital setting is crucial for expanding treatment options.
Purpose of the Study:
- To evaluate the feasibility and safety of performing Sonothrombolysis (ST) in a Chilean hospital.
- To determine the effectiveness of ST in achieving recanalization and functional outcomes in acute ischemic stroke patients.
Main Methods:
- Patients with acute ischemic stroke eligible for endovenous thrombolysis were studied using transcranial Doppler.
- Continuous monitoring with transcranial Doppler was performed on patients with adequate sonographic windows and demonstrated arterial occlusion, following the CLOTBUST protocol.
Main Results:
- 61 patients underwent Sonothrombolysis (ST), representing 7% of the total studied.
- Complete recanalization was achieved in 44.3% of patients, with 60% having a Modified Rankin Scale score of 0 to 2 at 3 months.
- Case fatality was 9.8%, and asymptomatic intracranial hemorrhage occurred in 9.8% of patients.
Conclusions:
- Sonothrombolysis (ST) can be successfully implemented in a complex medical center.
- ST is a safe and feasible treatment option for acute ischemic stroke patients in a Chilean healthcare setting.
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