Automatic analysis of heart rate variation: II. Findings in patients attending an EMG laboratory

An automatic method was used to measure the heart rate variation with breathing in patients with different neuromuscular conditions attending a laboratory of electromyography (EMG). The objective was to determine the frequency of abnormalities in various conditions and the relationship between R-R variation and different nerve conduction parameters. The percentages of reduced R-R variation were 73% in diabetics, 35% in Guillain-Barré syndrome, 22% in amyotrophic lateral sclerosis, and 50% in amyloidosis. R-R variation in diabetics was significantly correlated to most parameters of nerve conduction. In Guillain-Barré syndrome it correlated significantly with the ulnar and median M-response amplitudes. Most patients with myopathies showed normal R-R variation.