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Future options for ALK-positive non-small cell lung cancer

Daniela Iacono1, Rita Chiari2, Giulio Metro2

  • 1Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy; Medical Oncology, University of Rome 'La Sapienza', Sant'Andrea Hospital, Rome, Italy.

Lung Cancer (Amsterdam, Netherlands)
|January 21, 2015
PubMed
Summary

Targetable genetic alterations like anaplastic lymphoma kinase (ALK) rearrangements drive non-small cell lung cancer (NSCLC). ALK-tyrosine kinase inhibitors (TKIs) offer effective treatments, with newer drugs showing promise against resistance mechanisms.

Keywords:
ALKALK-TKIAlectinibCNS metastasesCeritinibCrizotinibNon-small cell lung cancerTargeted therapy

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