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Updated: Apr 18, 2026
Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
Gastric bypass improves survival compared with propensity-matched controls: a cohort study with over 10-year
Christopher A Guidry1, Stephen W Davies1, Robert G Sawyer1
1Department of Surgery, The University of Virginia Health System, Charlottesville, VA, USA.
Background:
The purpose of this study is to evaluate the long-term survival following gastric bypass using propensity-matched controls.
Methods:
We identified all patients who either received a gastric bypass (GBP) or met criteria to receive a GBP between January 1, 2002 and December 31, 2003. Propensity matching was performed. Long-term, all-cause mortality data were collected and evaluated using Kaplan-Meier curves.
Results:
Four hundred thirty GBP cases and 5,323 controls were identified from the enrollment period. Ultimately, 802 cases and controls (1:1 matching, 93.2% match rate) were identified using propensity matching. Median follow-up was similar between groups. Overall mortality was lower for the GBP group (odds ratio .48, 95% confidence interval .29 to .78). GBP demonstrated significantly increased survival when compared with controls (P = .002). Similar patterns were noted among diabetics.
Conclusion:
We have demonstrated that gastric bypass provides a clear long-term survival advantage compared with nonsurgical propensity-matched controls.
