Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

My Life as a Scientist: From RNA Polymerase to the Evolution of Beauty.

Annual review of genetics·2025
Same author

Effect of heterologous intranasal iNCOVACC<sup>®</sup> vaccination as a booster to two-dose intramuscular Covid-19 vaccination series: a randomized phase 3 clinical trial.

Communications medicine·2025
Same author

Spotting the band.

Proceedings of the National Academy of Sciences of the United States of America·2024
Same author

kcnj13 regulates pigment cell shapes in zebrafish and has diverged by cis-regulatory evolution between Danio species.

Development (Cambridge, England)·2023
Same author

Developmental genetics with model organisms.

Proceedings of the National Academy of Sciences of the United States of America·2022
Same author

The great small organisms of developmental genetics: Caenorhabditis elegans and Drosophila melanogaster.

Developmental biology·2022

Related Experiment Video

Updated: Apr 18, 2026

Reverse Genetic Approach to Identify Regulators of Pigmentation using Zebrafish
07:16

Reverse Genetic Approach to Identify Regulators of Pigmentation using Zebrafish

Published on: March 1, 2022

2.9K

Zebrafish stripes as a model for vertebrate colour pattern formation.

Ajeet Pratap Singh1, Christiane Nüsslein-Volhard1

  • 1Max-Planck-Institut für Entwicklungsbiologie, 72076 Tübingen, Germany.

Current Biology : CB
|January 21, 2015
PubMed
Summary

Zebrafish pigment cell interactions guide stripe formation. This study reveals molecular mechanisms of vertebrate color patterns, crucial for evolutionary variation.

More Related Videos

A Simple and Effective Transplantation Device for Zebrafish Embryos
06:59

A Simple and Effective Transplantation Device for Zebrafish Embryos

Published on: August 2, 2021

4.3K
High Resolution Whole Mount In Situ Hybridization within Zebrafish Embryos to Study Gene Expression and Function
10:06

High Resolution Whole Mount In Situ Hybridization within Zebrafish Embryos to Study Gene Expression and Function

Published on: October 19, 2013

23.4K

Related Experiment Videos

Last Updated: Apr 18, 2026

Reverse Genetic Approach to Identify Regulators of Pigmentation using Zebrafish
07:16

Reverse Genetic Approach to Identify Regulators of Pigmentation using Zebrafish

Published on: March 1, 2022

2.9K
A Simple and Effective Transplantation Device for Zebrafish Embryos
06:59

A Simple and Effective Transplantation Device for Zebrafish Embryos

Published on: August 2, 2021

4.3K
High Resolution Whole Mount In Situ Hybridization within Zebrafish Embryos to Study Gene Expression and Function
10:06

High Resolution Whole Mount In Situ Hybridization within Zebrafish Embryos to Study Gene Expression and Function

Published on: October 19, 2013

23.4K

Area of Science:

  • Developmental Biology
  • Evolutionary Biology
  • Genetics

Background:

  • Animal color patterns are vital for communication, camouflage, and reproduction.
  • Understanding the molecular basis of vertebrate color pattern formation remains a challenge.

Purpose of the Study:

  • To investigate the cellular and molecular mechanisms underlying the development of zebrafish (Danio rerio) striped color patterns.
  • To identify key cell types and molecular interactions involved in pattern formation.

Main Methods:

  • Utilized zebrafish as a model organism due to its genetic tractability and distinct color patterns.
  • Employed lineage tracing to track pigment cell origins and behaviors.
  • Conducted mutant analysis to identify genes and molecular pathways regulating pattern development.

Main Results:

  • Identified the origins and behaviors of xanthophores, iridophores, and melanophores during stripe formation.
  • Demonstrated that interactions between all three pigment cell types are essential for pattern development.
  • Discovered cell surface molecules and signaling systems mediating these crucial cell interactions.

Conclusions:

  • Zebrafish pigment cell interactions are fundamental to establishing complex color patterns.
  • This research provides insights into the genetic basis of evolutionary color variation in vertebrates.