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Author Spotlight: Advancing Prostate Cancer Research Through Improved Tissue Sampling and Biobanking
Published on: November 17, 2023
Comparative histopathological characterization of prostate cancer in Saudi patients by conventional and 2005 ISUP
Entissar Sulaiman Al Suhaibani1, Nadeem Abbas Kizilbash, Fatima Al Beladi
1Department of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia
Background:
The aim of this study was to compare the characterization of prostate cancer using the conventional and 2005 ISUP modified Gleason systems.
Materials And Methods:
The study employed samples from 40 prostate cancer patients with resection, biopsy and RP materials. The majority of cases (95%) comprised adenocarcinoma of the prostate with a modified combined Gleason score of 7 in 20 of the cases (50%).
Results:
Upgrading of Gleason scores to a score of 7 occurred in more than 45% of the cases.
Conclusion:
The study successfully showed that by the use of the 2005 ISUP modified Gleason system, score 6 cancers decreased from 25% to 17.5% of cases, whereas score 7 cancers increased from 45% to 50%.
