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Updated: Apr 18, 2026

Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System
Published on: May 12, 2011
Bilateral traumatic globe luxation with optic nerve transection
Levent Tok1, Ozlem Yalcin Tok1, Tugba Cakmak Argun1
1Department of Ophthalmology, Faculty of Medicine, Süleyman Demirel University, Isparta, Burdur, Turkey.
Purpose:
The purpose of this study was to document clinical findings and management of a patient with bilateral globe luxation and optic nerve transection.
Materials And Methods:
A 25-year-old female patient was admitted to the emergency department with bilateral traumatic globe luxation following a motor vehicle accident.
Results:
Visual acuity testing showed no light perception. The right pupil was dilated and bilaterally did not react to light. The globes were bilaterally intact. A computed tomography scan revealed Le Fort type II fractures, bilateral optic nerve transection and disruption of all extraocular muscles. The globes of the patient were bilaterally reduced into the orbit. However, the patient developed phthisis bulbi in the right eye at month 3.
Conclusion:
Globe luxation presents a dramatic clinical picture, and may lead to the development of severe complications due to the concomitance of complete optic nerve dissection and multiple traumas. Even if the luxated globe is repositioned into the orbit, there is still an increased risk of the development of phthisis due to ischemia.
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