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Haff disease complicated by multiple organ failure after crayfish consumption: a case study

Gang Feng1, Qiancheng Luo1, Ping Zhuang1

  • 1Intensive Care Unit, Gongli Hospital, Second Military Medical University, Shanghai, China.

Revista Brasileira De Terapia Intensiva
|January 22, 2015
PubMed

Insights

Haff disease, a rare condition causing rhabdomyolysis, can lead to multiple organ failure. This case highlights the severe risks of Haff disease following crayfish consumption.

Area of Science:

  • Toxicology
  • Nephrology
  • Gastroenterology

Background:

  • Haff disease is an unexplained syndrome characterized by rhabdomyolysis, often linked to consuming fish.
  • While typically self-limiting, severe complications can arise, necessitating further investigation into its etiology and clinical spectrum.

Observation:

  • A 66-year-old male presented with rhabdomyolysis and multiple organ failure after consuming cooked crayfish.
  • This represents the first documented case of Haff disease complicated by multiple organ failure attributed to crayfish ingestion.

Findings:

  • The patient was diagnosed with Haff disease complicated by multiple organ failure.
  • Despite intensive care and supportive treatment, the patient's condition worsened, leading to mortality.

Implications:

  • This case underscores the potential for severe Haff disease presentations beyond typical fish consumption.
  • Highlights the critical need for early diagnosis and prompt management to prevent fatal outcomes.
  • Suggests that crayfish may be a potential source of the toxin responsible for Haff disease.

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