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Expression of the bovine leukemia virus transactivator protein p34 by a recombinant vaccinia virus
L Willems1, C Letellier, M Gonze
1Faculty of Agronomy, Gembloux, Belgium.
Veterinary Immunology and Immunopathology
|October 1, 1989
Abstract:
In order to characterize the bovine leukemia virus transactivator protein, a recombinant vaccinia virus (v-LOR) containing the BLV post-envelope long open reading frame was constructed. v-LOR was shown to encode a functional protein able to transactivate the BLV long terminal repeat-directed gene expression in the infected cells. The encountered level of transactivation was about one third of that measured in BLV-infected fetal lamb kidney cell lysates.