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Predicting long-term outcomes of acute aortic dissection: a focus on gender

Dimitar Divchev1, Tarek Najjar, Falko Tillwich

  • 1Department of Cardiology, Heart Center, University Hospital Rostock, D-18057 Rostock, Germany.

Expert Review of Cardiovascular Therapy
|January 23, 2015
PubMed

Insights

Women face higher risks for acute aortic dissection and related complications compared to men. This review examines gender differences in aortic dissection

Area of Science:

  • Cardiovascular Medicine
  • Vascular Surgery
  • Epidemiology

Background:

  • Acute aortic disease is a significant cause of mortality, with increasing incidence.
  • Aortic rupture mortality is approximately 80%.
  • While traditionally affecting men more, gender ratios in aortic disease vary.

Purpose of the Study:

  • To review current evidence on the impact of gender on acute aortic dissection.
  • To analyze gender-specific differences in natural history, treatment, and outcomes.

Main Methods:

  • Literature review of current evidence.
  • Analysis of data from the International Registry of Acute Aortic Dissections (IRAD).

Main Results:

  • Women with acute aortic dissection have a higher risk of mortality and complications than men.
  • Significant gender-related differences exist in the management of acute aortic conditions.

Conclusions:

  • Gender is a critical factor influencing outcomes in acute aortic dissection.
  • Further research is needed to address gender disparities in acute aortic disease management and outcomes.

Keywords:
TAAaortic dissectiongenderoutcomethoracic endovascular stent-graft repair

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