[Dynamics of the blood serum protein fractions in patients with insulinoma]

Gel electrophoresis was used to study the blood serum of 13 patients with insulinomas who showed marked dysproteinemia in the preoperative period. Enucleation of the tumour or resection of the pancreas were performed depending on the location of the tumours. In the immediate postoperative period dysproteinemia became more pronounced, then a tendency to normalization of the protein spectrum occurred. Dysproteinemia was most pronounced at the zone of the starting peak where insulin-binding proteins are located.