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[Clinical and neurophysiologic tests in the normal elderly].

G Paradiso, F Micheli, I Casas Parera

    Neurologia (Barcelona, Spain)
    |March 1, 1989
    PubMed
    Summary

    Changes in ankle reflexes and vibration sense in the elderly are common but not due to peripheral nerve damage. These age-related sensory changes do not indicate an "aging neuropathy".

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    Area of Science:

    • Gerontology
    • Neuroscience
    • Clinical Neurology

    Context:

    • Age-related changes in sensory perception and reflexes are common in older adults.
    • Previous assumptions suggested peripheral nerve involvement might explain these changes.
    • Understanding the underlying mechanisms is crucial for accurate diagnosis and care.

    Purpose:

    • To investigate the relationship between clinical neurological findings and peripheral nerve function in healthy aged individuals.
    • To determine if age-related reflex and sensory deficits are associated with peripheral nerve abnormalities.
    • To evaluate the evidence for a distinct
    • aging neuropathy
    • .

    Summary:

    • Clinical and neurophysiological assessments were conducted on 35 healthy older adults (mean age 72).
    • Abnormalities in ankle reflexes (48.6%) and vibration sense (17%) were observed in a significant portion of subjects.
    • However, electromyography, motor conduction, sural nerve conduction velocity, and sensory evoked potentials were normal, indicating no peripheral nerve involvement.

    Impact:

    • The findings suggest that age-related declines in reflexes and vibration sense are not caused by peripheral nerve damage.
    • This research challenges the concept of an
    • aging neuropathy
    • as a distinct clinical entity.
    • Highlights the need to differentiate normal aging processes from pathological conditions in geriatric neurology.

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