[Pathologic analysis of primary hepatocellular carcinoma in 19 cases surviving over 10 years]

Pathological study was undertaken in 19 PHC patients who had survived over 10 years after operation. The pathological characteristics of the specimens were as follows: (1) Tumors less than 5 cm in diameter accounted for 78.9% (15/19), of which 13 PHC less than or equal to 3 cm in diameter. (2) Solitary tumors were found in 78.9% (15/19). (3) Sixteen out of nineteen (84.2%) cases had peritumor-fibrous encapsulation, and 13 cases had fibrolamellar structures in cancerous foci. (4) 14 out of 19(73.7%) cases were found to have lympholeukocyte infiltration in cancerous foci or encapsulation. (5) Liver cirrhosis was found in only 42.1% (8/19) of all cases and 75% of them were slight cirrhosis. These were the pathological background accounting for long survival duration of PHC patients. The authors suggest that early detection, diagnosis, and treatment be done in this period, for better opportunity of survival in PHC patients.