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Related Concept Videos

Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

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Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
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Acute Pyelonephritis I: Introduction01:27

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Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Brain Abscess l: Introduction01:26

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A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial...
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A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
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A urine culture and sensitivity test is a diagnostic procedure used to identify urinary tract bacterial infections and determine the most effective antibiotics for treatment. This test is generally preferred when a patient shows manifestations of a urinary tract infection, such as frequent or painful urination, cloudy or foul-smelling urine, or lower abdominal pain.Purpose of the TestThe primary goals of a urine culture and sensitivity test are to:Determine the specific bacteria causing the...
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Candida glabrata perinephric abscess.

Ilker Inanc Balkan1, Arif Savas2, Ayfer Geduk2

  • 1Department of Infectious Diseases and Clinical Microbiology, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey.

The Eurasian Journal of Medicine
|January 23, 2015
PubMed
Summary

A rare Candida glabrata perinephric abscess occurred in a diabetic patient. Prompt diagnosis with imaging and treatment including drainage and antifungal medication resolved the infection.

Keywords:
Candida glabrataFluconazolePercutaneous drainagePerinephric abscess

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Area of Science:

  • Nephrology
  • Infectious Diseases
  • Mycology

Background:

  • Perinephric abscess is a rare urinary tract infection complication, typically caused by gram-negative bacteria.
  • Candida glabrata, a yeast, is an uncommon cause of perinephric abscess, particularly in patients with underlying conditions.

Observation:

  • A case of Candida glabrata perinephric abscess in a diabetic patient with a history of pyelonephritis treated with antibiotics is presented.
  • The patient's symptoms were insidious, highlighting the need for a high index of suspicion in specific patient populations.

Findings:

  • Percutaneous drainage combined with fluconazole treatment successfully resolved the yeast perinephric abscess.
  • Diagnosis required contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI).

Implications:

  • Yeast perinephric abscess should be considered in elderly and diabetic patients with urinary tract infection symptoms unresponsive to antibiotics.
  • Early diagnosis via imaging and prompt treatment involving drainage and tailored antifungal therapy are crucial for successful outcomes.
  • Antifungal susceptibility testing is recommended to guide adjuvant antifungal treatment.