Related Experiment Video
Updated: Apr 18, 2026

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
Published on: July 5, 2022
Cost-effectivity analysis of one-step versus two-step screening for gestational diabetes
Sevki Celen1, Yasemin Yildiz2, Serkan Kahyaoglu1
1Department of High Risk Pregnancy, Zekai Tahir Burak Women's Health and Research Hospital, Ankara, Turkey.
Objective:
Early diagnosis of gestational diabetes mellitus (GDM) is important for both maternal and fetal health. The literature has varying recommendations about one-step and two-step tests for GDM screening and diagnosis. The present study aimed to investigate the difference in the cost and duration of hospital stay of a one-step procedure compared to a two-step procedure, which is routinely performed in our hospital.
Materials And Methods:
The two-step procedure was performed in 2,724 pregnant women, and the one-step procedure was performed in 185 pregnant women. The one-step and two-step screening procedures for gestational diabetes were compared with respect to the duration of hospital stay and cost.
Results:
The test cost per woman was 0.75 TL less in the one-step procedure; however, the duration of the one-step test was 18.6 min longer, and the number of blood sampling procedures was 1.08 times higher.
Conclusion:
The one-step method may be preferred over the two-step (or glucose challenge) test due to its diagnostic value and lower cost.
More Related Videos
Related Concept Videos
Diabetes Mellitus: Type 2 and Gestational
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...

