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Published on: September 12, 2020
Metoclopramide-induced acute dystonic reaction: a case report
Gul Karagoz1, Ayten Kadanali1, Behiye Dede1
1Department of Infectious Disease and Clinical Microbiology, Umraniye Training and Research Hospital, Istanbul, Turkey.
Abstract:
The aim of this case report is to draw attention to the frequent occurrence of metoclopramide-induced movement disorders. We report a case of an acute dystonic reaction to metoclopramide in a patient treated for hepatitis A. Metoclopramide can cause severe adverse events, such as an acute dystonic reaction, and should be used with caution in patients with infectious diseases.
Insights
Metoclopramide can cause acute dystonic reactions, a type of movement disorder. Healthcare providers should use metoclopramide cautiously, especially in patients with infectious diseases like hepatitis A.
Area of Science:
- Pharmacology
- Neurology
- Hepatology
Background:
- Metoclopramide is a commonly prescribed medication for gastrointestinal issues.
- Movement disorders are potential adverse effects of metoclopramide.
- Infectious diseases may alter drug metabolism and patient susceptibility to adverse events.
Observation:
- A case report details an acute dystonic reaction in a patient treated for hepatitis A.
- The patient received metoclopramide for their condition.
- The reaction manifested as an acute dystonic episode.
Findings:
- Metoclopramide administration led to an acute dystonic reaction.
- This adverse event highlights a known side effect of the drug.
- The occurrence in the context of hepatitis A warrants attention.
Implications:
- Clinicians should be aware of the risk of metoclopramide-induced movement disorders.
- Caution is advised when prescribing metoclopramide to patients with infectious diseases.
- Further investigation into drug interactions and patient-specific risks may be necessary.

