Metoclopramide-induced acute dystonic reaction: a case report

Gul Karagoz1, Ayten Kadanali1, Behiye Dede1

  • 1Department of Infectious Disease and Clinical Microbiology, Umraniye Training and Research Hospital, Istanbul, Turkey.

Insights

Metoclopramide can cause acute dystonic reactions, a type of movement disorder. Healthcare providers should use metoclopramide cautiously, especially in patients with infectious diseases like hepatitis A.

Area of Science:

  • Pharmacology
  • Neurology
  • Hepatology

Background:

  • Metoclopramide is a commonly prescribed medication for gastrointestinal issues.
  • Movement disorders are potential adverse effects of metoclopramide.
  • Infectious diseases may alter drug metabolism and patient susceptibility to adverse events.

Observation:

  • A case report details an acute dystonic reaction in a patient treated for hepatitis A.
  • The patient received metoclopramide for their condition.
  • The reaction manifested as an acute dystonic episode.

Findings:

  • Metoclopramide administration led to an acute dystonic reaction.
  • This adverse event highlights a known side effect of the drug.
  • The occurrence in the context of hepatitis A warrants attention.

Implications:

  • Clinicians should be aware of the risk of metoclopramide-induced movement disorders.
  • Caution is advised when prescribing metoclopramide to patients with infectious diseases.
  • Further investigation into drug interactions and patient-specific risks may be necessary.

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