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Updated: Apr 18, 2026

FISH for Pre-implantation Genetic Diagnosis
Published on: February 23, 2011
Chromosomal Translocation t (10;19) (q11.2;q13.4) in an Infertile Male
Murat Kara1, Askin Sen2, Esin Sakallı Cetin3
1Department of Medical Genetics, Mugla Sitki Kocman University Faculty of Medicine, Mugla, Turkey.
Abstract:
Chromosomal rearrangements are usually associated with male factor infertility. We report here a 34-year-old man suffering from primary infertility for 15 years. The cytogenetic analysis and investigation of Y-chromosome microdeletions were performed. A reciprocal balanced translocation t (10;19) (q11.2;q13.4) was found in oligozoospermic infertile men with no Y-chromosome microdeletions. In this case, we aimed to evaluate the 46,XY,t (10;19) (q11.2;q13.4) karyo-type, which was detected through a cytogenetic analysis of a person referred to our genetic laboratory due to primary infertility, in the light of the literature.
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