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Updated: Apr 18, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
The possibilities and principles of methotrexate treatment of psoriasis - the updated knowledge
Magdalena Czarnecka-Operacz1, Anna Sadowska-Przytocka2
1Department of Dermatology, Poznan University of Medical Sciences, Poznan, Poland. Head of the Department: Prof. Zygmunt Adamski MD, PhD ; Laboratory of Allergic Skin Diseases, Poznan University of Medical Sciences, Poznan, Poland. Head of the Laboratory: Prof. Magdalena Czarnecka-Operacz.
Abstract:
Psoriasis is a chronic multifactorial disease affecting 2-4% of the general population. Due to its nature, psoriasis has a negative impact on the quality of life of patients. Therefore, the choice of an appropriate and individually tailored treatment controlling the symptoms of the disorder is necessary and continues to be a challenge for dermatologists. Therapeutic modalities in psoriasis should on the one hand be effective and on the other hand present a good safety profile. Methotrexate (MTX) is one of treatment options for psoriasis and can be administered both as monotherapy or in combination schemes. The paper presents the current state of knowledge about the possible treatment of psoriatic patients with MTX according to contemporary guidelines.
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