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Updated: Apr 18, 2026

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
Published on: October 10, 2025
Segmental neurofibromatosis
Michał Sobjanek1, Magdalena Dobosz-Kawałko2, Igor Michajłowski1
1Department of Dermatology, Venereology and Allergology, Medical University of Gdansk, Gdansk, Poland. Head of the Department: Prof. Roman Nowicki MD, PhD.
Abstract:
Segmental neurofibromatosis or type V neurofibromatosis is a rare genodermatosis characterized by neurofibromas, café-au-lait spots and neurofibromas limited to a circumscribed body region. The disease may be associated with systemic involvement and malignancies. The disorder has not been reported yet in the Polish medical literature. A 63-year-old Caucasian woman presented with a 20-year history of multiple, flesh colored, dome-shaped, soft to firm nodules situated in the right lumbar region. A histopathologic evaluation of three excised tumors revealed neurofibromas. No neurological and ophthalmologic symptoms of neurofibromatosis were diagnosed.
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