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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
Russell body duodenitis with immunoglobulin kappa light chain restriction
William R Munday1, Lucy Harn Kapur1, Mina Xu1
1William R Munday, Lucy Harn Kapur, Mina Xu, Xuchen Zhang, Department of Pathology, Yale University School of Medicine, New Haven, CT 06516, United States.
Abstract:
Russell bodies are eosinophilic intracytoplasmic globules which are likely the result of disturbed secretion of immunoglobulins that accumulate within the plasma cell. Russell body collections have been identified within the stomach, known as Russell body gastritis. Similar lesions within the duodenum are referred to as Russell body duodenitis, which is rare. Several Russell body gastritis case reports are associated with Helicobacter pylori. However, the etiology of Russell body duodenitis remains unclear. Here we report the first case of Russell body duodenitis with immunoglobulin light chain restriction in a background of peptic duodenitis.
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