Related Experiment Video
Updated: Apr 18, 2026
15:49
Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
Published on: October 16, 2013
33.0K
Acute onset collagenous colitis with unique endoscopic findings
Rintaro Moroi1, Katsuya Endo1, Masatake Kuhroha1
1Division of Gastroenterology, Department of Internal Medicine, Tohoku University Graduate School of Medicine, 1-1 Seiryo, Aoba-ku, Sendai 980-8574, Japan.
Case Reports in Gastrointestinal Medicine
|January 23, 2015
Summary
A rare case of acute collagenous colitis (CC) in a 72-year-old woman was triggered by lansoprazole, presenting with unusual symptoms like melena. Colonoscopy is crucial for differentiating this from ischemic colitis.
Area of Science:
- Gastroenterology
- Colorectal Diseases
- Drug-Induced Conditions
Background:
- Collagenous colitis (CC) is a rare condition often presenting with chronic watery diarrhea.
- Acute onset of CC is uncommon, and symptoms can mimic other gastrointestinal disorders.
Purpose of the Study:
- To report a rare case of acute collagenous colitis induced by lansoprazole.
- To highlight the diagnostic utility of colonoscopy in differentiating acute CC from ischemic colitis.
Main Methods:
- Case report of a 72-year-old woman with acute onset gastrointestinal symptoms.
- Colonoscopic examination revealing active "long liner" ulcers.
- Observation of the healing process of the observed colonic findings.
Main Results:
- The patient presented with acute abdominal pain, watery diarrhea, and melena, atypical for CC.
- Colonoscopy identified characteristic active "long liner" ulcers.
- The observed lesions demonstrated a healing course.
Conclusions:
- Collagenous colitis can present with acute symptoms, mimicking ischemic colitis.
- Colonoscopy is essential for accurate diagnosis and differentiation between acute CC and ischemic colitis.
More Related Videos
Related Concept Videos
01:20Inflammatory Bowel Disease II: Ulcerative Colitis
3
Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal...
3
01:26Inflammatory Bowel Disease I: Introduction
4
Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows...
4
01:30Inflammatory Bowel Disease II: Crohn's Disease
1.6K
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
1.6K
01:27Inflammatory Bowel Disease I: Ulcerative Colitis
1.6K
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
1.6K
01:17Chronic Bowel Disorders: Introduction
958
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
958
01:20Inflammatory Bowel Disease IV: Clinical Manifestations
1
Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The...
1