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Updated: Apr 18, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
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A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

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Sequential maximum androgen blockade (MAB) in minimally symptomatic prostate cancer progressing after initial MAB:

Mohan Hingorani1, Sanjay Dixit1, Fahim Bashir1

  • 11 Department of Clinical Oncology, Castle Hill Hospital, Cottingham, HU16 5JQ, UK ; 2 Department of Urology, Scarborough General Hospital, Scarborough, YO12 6QL, UK.

Cancer Biology & Medicine
|January 23, 2015
PubMed
Summary

Rechallenging patients with castrate-resistant prostate cancer using the same anti-androgen after a break shows sustained biochemical response. This sequential therapy approach offers a novel strategy for managing advanced prostate cancer.

Keywords:
Prostate cancercastrate resistancemaximum androgen blockade (MAB)

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