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Functional Assessment of Intestinal Permeability and Neutrophil Transepithelial Migration in Mice using a Standardized Intestinal Loop Model
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Connecting metabolism to intestinal barrier function: The role of leptin

Gwenola Le Dréan1, Jean-Pierre Segain1

  • 1Université de Nantes; Institut des Maladies de l'Appareil Digestif (IMAD); Centre de Recherche en Nutrition Humaine du Grand Ouest (CRNH) ; Nantes, France ; CHU Hôtel-Dieu, Place Alexis Ricordeau ; Nantes, France.

Tissue Barriers
|January 23, 2015
PubMed

Keywords:
AMPKAMPK, AMP-activated protein kinaseIEB, intestinal epithelial barrierIEC, intestinal epithelial cellsJAK, Janus kinaseJAK/STATLepR-b, leptin receptorMEF, mouse embryonic fibroblastMLC, myosin light chainROCK, Rho-kinaseRhoA/ROCKSTAT, signal transducer and activator of transcriptionTJ, tight junctionsVAT, visceral adipose tissuebarrier repairintestinal epithelial barrierleptinmetabolismtight-junction

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