Related Experiment Video
Updated: Apr 18, 2026

Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation
Published on: September 24, 2021
Ventricular pacing for induced hypotension in a toddler
Kelly A Machovec1, Edmund H Jooste, Warwick A Ames
1From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina.
Rapid ventricular pacing effectively induced controlled hypotension in an 18-month-old child undergoing brain aneurysm clipping. This neurosurgical technique offers a non-pharmacologic alternative for pediatric patients.
Area of Science:
- Neurosurgery
- Pediatric Anesthesiology
- Cardiovascular Physiology
Background:
- Cerebral aneurysm clipping often necessitates controlled hypotension to aid surgical dissection and clip placement.
- Pharmacologic agents are typically used to induce hypotension, posing potential risks, especially in pediatric cases.
Purpose of the Study:
- To describe the novel application of rapid ventricular pacing for controlled hypotension in a pediatric neurosurgical procedure.
- To present an alternative to pharmacologic hypotension for facilitating cerebral aneurysm clipping in infants.
Main Methods:
- The study details the use of rapid ventricular pacing in an 18-month-old child undergoing surgery for a giant basilar artery aneurysm.
- This method was employed to achieve controlled hypotension, aiding the neurosurgical intervention.
Main Results:
- Rapid ventricular pacing successfully facilitated the establishment of controlled hypotension during the complex neurosurgical procedure.
- The technique proved effective in the pediatric patient, allowing for necessary surgical conditions.
Conclusions:
- Rapid ventricular pacing is a viable, non-pharmacologic alternative for inducing controlled hypotension in pediatric neurosurgery.
- This method has not been previously documented in children for cerebral aneurysm clipping and offers a promising approach.
More Related Videos
Related Concept Videos
Dysrhythmias VI: Management of Dysrhythmias
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias
Cardiopulmonary Resuscitation IV: Pharmacological Management
Dysrhythmias VII: Nursing Management of Dysrhythmias
Decreased pulse rate
There are specific risk factors that can elevate the likelihood of developing bradycardia. Advanced age is a significant factor, with...
Dysrhythmias IV: Characteristics of Bradyarrhythmias

