Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A sensation driven functional MRI study on brain activation during bladder filling in healthy participants.

Scientific reports·2025
Same author

Detrusor Underactivity and Acontractile Bladder Patients Performing Clean Intermittent Catheterization in a Single Tertiary Referral Center: What is Happening in Real Life?

International urogynecology journal·2025
Same author

Correction: Prolonged opioid use after single-level lumbar spinal fusion surgery in a Belgian population: a multicentric observational study.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2025
Same author

Can EEG-Neurofeedback Training Enhance Effective Connectivity in People With Chronic Secondary Musculoskeletal Pain? A Secondary Analysis of a Feasibility Randomized Controlled Clinical Trial.

Brain and behavior·2025
Same author

Mourning for Silence: Bereavement and Tinnitus-A Perspective.

Journal of clinical medicine·2025
Same author

Infraslow Closed-Loop Brain Training for Anxiety and Depression (ISAD): A pilot randomised, sham-controlled trial in adult females with internalizing disorders.

Cognitive, affective & behavioral neuroscience·2025

Related Experiment Video

Updated: Apr 18, 2026

A Protocol for the Administration of Real-Time fMRI Neurofeedback Training
07:05

A Protocol for the Administration of Real-Time fMRI Neurofeedback Training

Published on: August 24, 2017

11.6K

Stress-Related Functional Connectivity Changes Between Auditory Cortex and Cingulate in Tinnitus.

Sven Vanneste1,2, Dirk De Ridder3,4

  • 11 Lab for Clinical and Integrative Neuroscience, School of Behavioral and Brain Sciences, The University of Texas at Dallas , Dallas, Texas.

Brain Connectivity
|January 23, 2015
PubMed
Summary
This summary is machine-generated.

Functional connectivity in the brain

Keywords:
distressseed-based connectivitystate dependenttinnitus

More Related Videos

Mapping the After-effects of Theta Burst Stimulation on the Human Auditory Cortex with Functional Imaging
10:09

Mapping the After-effects of Theta Burst Stimulation on the Human Auditory Cortex with Functional Imaging

Published on: September 12, 2012

14.4K
Functional Imaging of Auditory Cortex in Adult Cats using High-field fMRI
10:50

Functional Imaging of Auditory Cortex in Adult Cats using High-field fMRI

Published on: February 19, 2014

12.1K

Related Experiment Videos

Last Updated: Apr 18, 2026

A Protocol for the Administration of Real-Time fMRI Neurofeedback Training
07:05

A Protocol for the Administration of Real-Time fMRI Neurofeedback Training

Published on: August 24, 2017

11.6K
Mapping the After-effects of Theta Burst Stimulation on the Human Auditory Cortex with Functional Imaging
10:09

Mapping the After-effects of Theta Burst Stimulation on the Human Auditory Cortex with Functional Imaging

Published on: September 12, 2012

14.4K
Functional Imaging of Auditory Cortex in Adult Cats using High-field fMRI
10:50

Functional Imaging of Auditory Cortex in Adult Cats using High-field fMRI

Published on: February 19, 2014

12.1K

Area of Science:

  • Neuroscience
  • Medical Imaging
  • Auditory Neuroscience

Background:

  • Chronic tinnitus is often accompanied by distress and loudness perception.
  • Understanding the neural networks underlying tinnitus is crucial for developing effective treatments.

Purpose of the Study:

  • To investigate if functional connectivity (FC) changes between distress and tinnitus loudness networks during resting state are dependent on the level of distress experienced by patients.
  • To explore the relationship between tinnitus loudness, distress, and brain activity using electroencephalography (EEG).

Main Methods:

  • Fifty-five patients with chronic tinnitus underwent resting-state EEG recordings.
  • Seed-based source-localized functional connectivity (lagged phase synchronization) was computed across different EEG frequency bands.
  • Analysis focused on the auditory cortex and its connections with distress-related brain regions.

Main Results:

  • The correlation between tinnitus loudness and distress was found to be nonlinear.
  • Loudness correlated with beta3 and gamma band activity in auditory cortices; distress correlated with alpha1 and beta3 changes in cingulate cortex regions.
  • Significant differences in FC were observed between tinnitus patients and controls, particularly in alpha1 and beta3 bands, involving auditory cortex, posterior cingulate cortex, parahippocampal area, anterior cingulate, and insula.
  • Distress modulated FC between the auditory cortex (loudness encoding) and cingulate regions (distress encoding) in specific frequency bands (alpha1, beta3).

Conclusions:

  • Tinnitus involves multiple interacting neural networks, with distress dynamically altering the functional connectivity between loudness and distress processing areas.
  • These findings support a dynamic network model of tinnitus, emphasizing the interplay of correlations and anti-correlations based on individual distress levels.
  • The study highlights the specific roles of alpha1 and beta3 frequency bands in mediating distress-related functional connectivity changes in tinnitus.