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Updated: Apr 18, 2026

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy
Published on: June 1, 2019
The history of sentinel lymph node biopsy
Omgo E Nieweg1, Roger F Uren, John F Thompson
1From the *Melanoma Institute Australia and †The Mater Hospital, North Sydney; ‡Royal Prince Alfred Hospital, Camperdown; §Sydney Medical School, The University of Sydney; ∥Nuclear Medicine and Diagnostic Ultrasound, Newtown, New South Wales, Australia.
Abstract:
The sentinel node biopsy technique, developed by Drs Donald Morton and Alistair Cochran and reported in 1992, undoubtedly constitutes the most important recent development in surgical oncology. This article describes the evolution of the procedure and its contribution to the evolution of modern multidisciplinary cancer care and discusses its present role in the management of patients with melanoma, breast cancer, and a wide range of other malignancies.

