[Phenolic compounds from Rhododendron phaeochrysum var. agglutinatum]

Area of Science:

• Phytochemistry
• Natural Product Chemistry

Context:

• Rhododendron species are known for their diverse secondary metabolites.
• Rhododendron phaeochrysum var. agglutinatum is a plant with potential pharmacological interest.

Purpose:

• To isolate and identify phenolic compounds from Rhododendron phaeochrysum var. agglutinatum.
• To characterize novel and previously unreported compounds from this plant species.

Summary:

• Eight phenolic compounds were successfully isolated and structurally elucidated.
• Phaeochrysin (1) was identified as a new compound.
• Compounds 2, 5, 6, 7, and 8 were reported from this plant for the first time, including (2R)-4-(3',4'-dihydroxyphenyl)-2-butanol, (+)-isolariciresinol, (-)-lyoniresinol, lyoniresinol-9'-O-β-D-xylopyranoside, and dihydrodehydrodiconiferyl-3a-O-α-L-rhamnopyranoside.

Impact:

• Enriches the phytochemical database of Rhododendron species.
• Provides valuable chemical reference standards for further pharmacological investigations.
• Highlights the potential of Rhododendron phaeochrysum var. agglutinatum as a source of bioactive natural products.