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Updated: Apr 18, 2026
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Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
Published on: June 18, 2021
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[Depression remitted after subarachnoid haemorrhage].
1Psykiatrisk Afdeling O, Psykiatrisk Center København, Rigshospitalet, Edel Sauntes Alle 10, 2100 København Ø. liselau@hotmail.com.
Ugeskrift for Laeger
|January 24, 2015
Summary
Treatment-resistant depression in a 65-year-old man resolved spontaneously after a subarachnoid hemorrhage. This case highlights an unexpected remission from severe mood disorders following a cerebrovascular event.
Area of Science:
- Neuroscience
- Psychiatry
- Neurology
Background:
- Presents a case of a 65-year-old male with treatment-resistant depression.
- Details a three-year history of managing severe mood disorder symptoms.
Observation:
- Patient underwent extensive treatment with various antidepressants and mood stabilizers, including selective serotonin reuptake inhibitors, dual-action agents, lithium, nortriptyline, reboxetine, aripiprazole, benzodiazepines, isocarboxazide, and lamotrigine.
- No significant improvement was observed despite the comprehensive pharmacological interventions.
Findings:
- An abrupt resolution of psychiatric symptoms occurred following a subarachnoid hemorrhage.
- The patient maintained complete remission for 15 months post-hemorrhage, transitioning to general practitioner care.
Implications:
- Suggests a potential link between cerebrovascular events and the spontaneous remission of treatment-resistant depression.
- Underscores the complex interplay between neurological events and mood disorders.
- Warrants further investigation into the neurobiological mechanisms underlying depression remission post-hemorrhage.
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