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Updated: Apr 18, 2026

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
Published on: August 13, 2019
[Buschke-Ollendorff syndrome in two generations imitated Calvé-Legg-Perthes disease]
Nebras Ali, Sanne Fast, Mette Ramsdal Poulsen
1Hudafdeling I og Allergicentret, Odense Universitetshospital, Sdr. Boulevard 29, 5000 Odense C. anette.bygum@rsyd.dk.
Abstract:
Buschke-Ollendorff syndrome is a rare condition characterized by skin manifestations and osteopoikilosis. We describe a mother and her son who presented with indurated skin lesions suggestive of connective tissue naevi. X-rays showed multiple symmetrical foci of osteosclerosis. They had both been diagnosed earlier with Calvé-Legg-Perthes disease, which on revision most likely represented Buschke-Ollendorff syndrome. Buschke-Ollendorff syndrome may imitate Calvé-Legg-Perthes disease. Skin signs may be the clue to diagnosis. Main differentials are sclerotic bone metastases and osteoma.
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